Effectiveness of doxycycline pre-exposure and post-exposure prophylaxis for the prevention of bacterial STI for populations disproportionately impacted by sexually transmitted infections

Cases and rates of bacterial sexually transmitted infections (STI), including gonorrhea, chlamydia and syphilis, have steadily increased over the last decade in Canada. This growing public health concern has focused attention on approaches to more effectively prevent STIs, particularly for the groups disproportionately affected by and/or at high risk for STI, including gay, bisexual and other men who have sex with men (gbMSM); transgender women (TGW); cisgender women (CGW), particularly Indigenous cisgender women; sex workers; people living with HIV; and people taking HIV pre-exposure prophylaxis (PrEP).