Examining what is known about the emergence, transmission and spectrum of the burden of disease of avian influenza A (H5Nx) subtypes

Jan 12, 2024 - Jul 17, 2024

Programs: Evidence syntheses

Avian influenza A (H5Nx) viruses have been reported globally, leading to large outbreaks in poultry, wild birds, and mammals. Recent H5 viruses have emerged or re-emerged, causing concern on the potential transmission and spectrum of the burden of disease in humans. This living evidence profile aims to identify the current state of evidence and knowledge gaps from existing evidence syntheses related to the emergence, transmission and spectrum of the burden of disease in humans of avian influenza as a first step towards informing prevention and mitigation interventions.

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Identifying features and impacts of public health strategies that can be used to prevent, reduce and/or mitigate avian influenza spillover to humans

Jan 12, 2024 - Jul 17, 2024

Programs: Evidence syntheses

Avian influenza is commonly found in birds, but it can also infect non-human mammals (e.g., cats, foxes, bears), and humans. As an emerging infectious disease with pandemic potential, it is important to identify effective upstream and downstream public health strategies (particularly those that adopt a One Health approach) to prevent, reduce, and/or mitigate the risk of avian spillover into humans. This rapid evidence profile was requested to inform initial deliberations about such public health strategies and therefore focused on identifying existing evidence syntheses where evidence from single studies was identified and synthesized.

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Examining what is known about the emergence, transmission and spectrum of the burden of disease of avian influenza A (H5Nx) subtypes